Choral Masters: These groups meet daily as a credit course.
Varsity Chorale: The Varsity Chorale is Euclid's show choir. These students perform at many community functions, competitions, as well as appear on television. This is also a credit class.
Voices of New Life Choir: The Voices of New Life sing gospel and inspirational songs. They perform at many community and school functions.
E. 222nd Street Jazz Band: This group performs at many community and school functions. At times, their attire consists of black sunglasses and black hats.
Orchestra: The Orchestra meets daily as a credit course. They perform concerts throughout the year.
Marching Band: The Marching Band meets daily as a credit course. They perform at football games and parades. In the winter and spring, members form the concert band and the symphonic ensemble.